Most
of the populations worldwide are suffering from some form of gum disease. Periodontal
diseases could be simple gum disease in worst they can damage soft tissue and
bone which support teeth.
What
is Periodontitis?
Periodontitis
is inflammation of gum and bone support surrounding the teeth. It forms pockets
and spaces between tooth and gum. It may worsen and cause loss of tooth.
Early
detection of periodontal disease is a challenge as it does not cause any pain
and may progress unnoticed. In its early stages, bleeding gums during tooth
brushing may be the only sign. With the progression of disease, bleeding may
stop and there may be no further obvious sign until the teeth start to feel
loose.
What
happens if gum disease left untreated?
Besides
tooth loss new medical study revealed periodontitis may trigger cardiopulmonary
disease, rheumatoid disease, COPD (Chronic obstructive pulmonary disorders) as
well as it leads to risk for Alzheimer’s. Bacteria in gum disease spread
through blood circulation causing above disease.
Based
on statistics found by World Health Organizations, more than 60% adults
suffering from gum disease and It is spreading in such manner so Researchers
are more keen to find preventing ways to stop spreading bacteria in the gums.
Study is being designed by Eleven European researchers from nine countries
through one project called TRIGGER. The goal of the study is to find the
connection between periodontitis and other inflammatory diseases and to
maintain oral hygiene to improve dental health.
Know
the mechanism of gingivitis leading to periodontitis
Gingivitis
is the inflammation of gums of the neck at the teeth. It can to lead to develop
periodontitis in future.Porphyromonas Gingivalis is the bacteria causing
gingivitis. The research is aimed for find active compound against these
bacteria.
Porphyromonas
Gingivalis, the bacteria in the oral cavity destroys the gum connective tissue
by stimulating protein degrading enzyme before release it into oral cavity.
Special enzyme, the bacterial glutaminyl cyclase which is occupied with protein
maturation. It is playing crucial role leading to inflammatory conditions such
as Rheumatoid arthritis, COPD and Alzheimer’s. The team of research is finding
the compounds which lessen the enzyme’s action.
The
study team could sort few substances which hamper the growth of bacteria. So
not just good oral hygiene is enough, but we have to find additional measures to
improve health and prevent from other inflammatory diseases.
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